Model Deployment : Classifying Brain Tumors from Magnetic Resonance Images by Leveraging Convolutional Neural Network-Based Multilevel Feature Extraction and Hierarchical Representation¶

John Pauline Pineda

November 30, 2024

  • 1. Table of Contents
    • 1.1 Data Background
    • 1.2 Data Description
    • 1.3 Data Quality Assessment
    • 1.4 Data Preprocessing
    • 1.5 Data Exploration
      • 1.5.1 Exploratory Data Analysis
      • 1.5.2 Hypothesis Testing
    • 1.6 Predictive Model Development
      • 1.6.1 Pre-Modelling Data Preparation
      • 1.6.2 Data Splitting
      • 1.6.3 Convolutional Neural Network Sequential Layer Development
        • 1.6.3.1 CNN With No Regularization
        • 1.6.3.2 CNN With Dropout Regularization
        • 1.6.3.3 CNN With Batch Normalization Regularization
        • 1.6.3.4 CNN With Dropout and Batch Normalization Regularization
      • 1.6.4 CNN With No Regularization Model Fitting | Hyperparameter Tuning | Validation
      • 1.6.5 CNN With Dropout Regularization Model Fitting | Hyperparameter Tuning | Validation
      • 1.6.6 CNN With Batch Normalization Regularization Model Fitting | Hyperparameter Tuning | Validation
      • 1.6.7 CNN With Dropout and Batch Normalization Regularization Model Fitting | Hyperparameter Tuning | Validation
      • 1.6.8 Model Selection
      • 1.6.9 Model Testing
      • 1.6.10 Model Inference
    • 1.7 Predictive Model Deployment Using Streamlit and Streamlit Community Cloud
      • 1.7.1 Model Application Programming Interface Code Development
      • 1.7.2 User Interface Application Code Development
      • 1.7.3 Web Application
  • 2. Summary
  • 3. References

1. Table of Contents ¶

1.1 Data Background ¶

1.2 Data Description ¶

In [1]:
##################################
# Loading Python Libraries
##################################

##################################
# Data Loading, Data Preprocessing
# and Exploratory Data Analysis
##################################
import numpy as np
import pandas as pd 
import seaborn as sns
import matplotlib.pyplot as plt
import matplotlib.image as mpimg
import matplotlib.cm as cm
from matplotlib.offsetbox import OffsetImage, AnnotationBbox
%matplotlib inline

import tensorflow as tf
import keras

from PIL import Image
from glob import glob
import cv2
import os
import random
import math

##################################
# Model Development
##################################
from keras import backend as K
from keras import regularizers
from keras.models import Sequential, Model,load_model
from keras.layers import Input, Activation, Dense, Dropout, Flatten, Conv2D, MaxPooling2D, MaxPool2D, AveragePooling2D, GlobalMaxPooling2D, BatchNormalization
from keras.optimizers import Adam, SGD
from keras.callbacks import ReduceLROnPlateau, EarlyStopping, ModelCheckpoint
from tensorflow.keras.preprocessing.image import ImageDataGenerator
from tensorflow.keras.utils import img_to_array, array_to_img, load_img

##################################
# Model Evaluation
##################################
from keras.metrics import PrecisionAtRecall, Recall 
from sklearn.metrics import confusion_matrix
from sklearn.metrics import precision_recall_fscore_support, accuracy_score
In [2]:
##################################
# Setting random seed options
# for the analysis
##################################
def set_seed(seed=123):
    np.random.seed(seed) 
    tf.random.set_seed(seed) 
    keras.utils.set_random_seed(seed)
    random.seed(seed)
    tf.config.experimental.enable_op_determinism()
    os.environ['TF_DETERMINISTIC_OPS'] = "1"
    os.environ['TF_CUDNN_DETERMINISM'] = "1"
    os.environ['PYTHONHASHSEED'] = str(seed)
set_seed()
In [3]:
##################################
# Filtering out unncessary warnings
##################################
import warnings
warnings.filterwarnings('ignore')
In [4]:
##################################
# Defining file paths
##################################
DATASETS_ORIGINAL_PATH = r"datasets\Brain_Tumor_MRI_Dataset"
DATASETS_FINAL_TRAIN_PATH = r"datasets\Brain_Tumor_MRI_Dataset\Training"
DATASETS_FINAL_TEST_PATH = r"datasets\Brain_Tumor_MRI_Dataset\Testing"
MODELS_PATH = r"models"
PARAMETERS_PATH = r"parameters"
PIPELINES_PATH = r"pipelines"
In [5]:
##################################
# Defining the image category levels
##################################
diagnosis_code_dictionary = {'Tr-no': 0,
                             'Tr-noTr': 0,
                             'Tr-gl': 1,
                             'Tr-glTr': 1,
                             'Tr-me': 2,
                             'Tr-meTr': 2,
                             'Tr-pi': 3,
                             'Tr-piTr': 3}

##################################
# Defining the image category descriptions
##################################
diagnosis_description_dictionary = {'Tr-no': 'No Tumor',
                                    'Tr-noTr': 'No Tumor',
                                    'Tr-gl': 'Glioma',
                                    'Tr-glTr': 'Glioma',
                                    'Tr-me': 'Meningioma',
                                    'Tr-meTr': 'Meningioma',
                                    'Tr-pi': 'Pituitary',
                                    'Tr-piTr': 'Pituitary'}

##################################
# Consolidating the image path
##################################
imageid_path_dictionary = {os.path.splitext(os.path.basename(x))[0]: x for x in glob(os.path.join("..", DATASETS_FINAL_TRAIN_PATH, '*','*.jpg'))}
In [6]:
##################################
# Taking a snapshot of the dictionary
##################################
dict(list(imageid_path_dictionary.items())[0:5])
Out[6]:
{'Tr-glTr_0000': '..\\datasets\\Brain_Tumor_MRI_Dataset\\Training\\glioma\\Tr-glTr_0000.jpg',
 'Tr-glTr_0001': '..\\datasets\\Brain_Tumor_MRI_Dataset\\Training\\glioma\\Tr-glTr_0001.jpg',
 'Tr-glTr_0002': '..\\datasets\\Brain_Tumor_MRI_Dataset\\Training\\glioma\\Tr-glTr_0002.jpg',
 'Tr-glTr_0003': '..\\datasets\\Brain_Tumor_MRI_Dataset\\Training\\glioma\\Tr-glTr_0003.jpg',
 'Tr-glTr_0004': '..\\datasets\\Brain_Tumor_MRI_Dataset\\Training\\glioma\\Tr-glTr_0004.jpg'}
In [7]:
##################################
# Consolidating the information
# from the dataset
# into a dataframe
##################################
mri_images = pd.DataFrame.from_dict(imageid_path_dictionary, orient = 'index').reset_index()
mri_images.columns = ['Image_ID','Path']
classes = mri_images.Image_ID.str.split('_').str[0]
mri_images['Diagnosis'] = classes
mri_images['Target'] = mri_images['Diagnosis'].map(diagnosis_code_dictionary.get) 
mri_images['Class'] = mri_images['Diagnosis'].map(diagnosis_description_dictionary.get)
In [8]:
##################################
# Performing a general exploration of the dataset
##################################
print('Dataset Dimensions: ')
display(mri_images.shape)

Dataset Dimensions: 

(5712, 5)
In [9]:
##################################
# Listing the column names and data types
##################################
print('Column Names and Data Types:')
display(mri_images.dtypes)

Column Names and Data Types:

Image_ID     object
Path         object
Diagnosis    object
Target        int64
Class        object
dtype: object
In [10]:
##################################
# Taking a snapshot of the dataset
##################################
mri_images.head()
Out[10]:
Image_ID Path Diagnosis Target Class
0 Tr-glTr_0000 ..\datasets\Brain_Tumor_MRI_Dataset\Training\g... Tr-glTr 1 Glioma
1 Tr-glTr_0001 ..\datasets\Brain_Tumor_MRI_Dataset\Training\g... Tr-glTr 1 Glioma
2 Tr-glTr_0002 ..\datasets\Brain_Tumor_MRI_Dataset\Training\g... Tr-glTr 1 Glioma
3 Tr-glTr_0003 ..\datasets\Brain_Tumor_MRI_Dataset\Training\g... Tr-glTr 1 Glioma
4 Tr-glTr_0004 ..\datasets\Brain_Tumor_MRI_Dataset\Training\g... Tr-glTr 1 Glioma
In [11]:
##################################
# Performing a general exploration of the numeric variables
##################################
print('Numeric Variable Summary:')
display(mri_images.describe(include='number').transpose())

Numeric Variable Summary:
count mean std min 25% 50% 75% max
Target 5712.0 1.465336 1.147892 0.0 0.0 1.0 3.0 3.0
In [12]:
##################################
# Performing a general exploration of the object variable
##################################
print('Object Variable Summary:')
display(mri_images.describe(include='object').transpose())

Object Variable Summary:
count unique top freq
Image_ID 5712 5712 Tr-pi_1440 1
Path 5712 5712 ..\datasets\Brain_Tumor_MRI_Dataset\Training\p... 1
Diagnosis 5712 8 Tr-no 1585
Class 5712 4 No Tumor 1595
In [13]:
##################################
# Performing a general exploration of the target variable
##################################
mri_images.Class.value_counts()
Out[13]:
Class
No Tumor      1595
Pituitary     1457
Meningioma    1339
Glioma        1321
Name: count, dtype: int64
In [14]:
##################################
# Performing a general exploration of the target variable
##################################
mri_images.Class.value_counts(normalize=True)
Out[14]:
Class
No Tumor      0.279237
Pituitary     0.255077
Meningioma    0.234419
Glioma        0.231268
Name: proportion, dtype: float64

1.3 Data Quality Assessment ¶

In [15]:
##################################
# Counting the number of duplicated images
##################################
mri_images.duplicated().sum()
Out[15]:
np.int64(0)
In [16]:
##################################
# Gathering the number of null images
##################################
mri_images.isnull().sum()
Out[16]:
Image_ID     0
Path         0
Diagnosis    0
Target       0
Class        0
dtype: int64

1.4 Data Preprocessing ¶

In [17]:
##################################
# Including the pixel information
# of the actual images
# in array format
# into a dataframe
##################################
mri_images['Image'] = mri_images['Path'].map(lambda x: np.asarray(Image.open(x).resize((200,200))))
In [18]:
##################################
# Listing the column names and data types
##################################
print('Column Names and Data Types:')
display(mri_images.dtypes)

Column Names and Data Types:

Image_ID     object
Path         object
Diagnosis    object
Target        int64
Class        object
Image        object
dtype: object
In [19]:
##################################
# Taking a snapshot of the dataset
##################################
mri_images.head()
Out[19]:
Image_ID Path Diagnosis Target Class Image
0 Tr-glTr_0000 ..\datasets\Brain_Tumor_MRI_Dataset\Training\g... Tr-glTr 1 Glioma [[[0, 0, 0], [0, 0, 0], [0, 0, 0], [0, 0, 0], ...
1 Tr-glTr_0001 ..\datasets\Brain_Tumor_MRI_Dataset\Training\g... Tr-glTr 1 Glioma [[[0, 0, 0], [0, 0, 0], [0, 0, 0], [0, 0, 0], ...
2 Tr-glTr_0002 ..\datasets\Brain_Tumor_MRI_Dataset\Training\g... Tr-glTr 1 Glioma [[[0, 0, 0], [0, 0, 0], [0, 0, 0], [0, 0, 0], ...
3 Tr-glTr_0003 ..\datasets\Brain_Tumor_MRI_Dataset\Training\g... Tr-glTr 1 Glioma [[[0, 0, 0], [0, 0, 0], [0, 0, 0], [0, 0, 0], ...
4 Tr-glTr_0004 ..\datasets\Brain_Tumor_MRI_Dataset\Training\g... Tr-glTr 1 Glioma [[[0, 0, 0], [0, 0, 0], [0, 0, 0], [0, 0, 0], ...
In [20]:
##################################
# Taking a snapshot of the dataset
##################################
n_samples = 5
fig, m_axs = plt.subplots(4, n_samples, figsize = (2*n_samples, 10))
for n_axs, (type_name, type_rows) in zip(m_axs, mri_images.sort_values(['Class']).groupby('Class')):
    n_axs[2].set_title(type_name, fontsize = 14, weight = 'bold')
    for c_ax, (_, c_row) in zip(n_axs, type_rows.sample(n_samples, random_state=123).iterrows()):       
        picture = c_row['Path']
        image = cv2.imread(picture)
        resized_image = cv2.resize(image, (500,500))
        c_ax.imshow(resized_image)
        c_ax.axis('off')
No description has been provided for this image
In [21]:
##################################
# Sampling a single image
##################################
samples, features = mri_images.shape
plt.figure()
pic_id = random.randrange(0, samples)
picture = mri_images['Path'][pic_id]
image = cv2.imread(picture) 

<Figure size 640x480 with 0 Axes>
In [22]:
##################################
# Plotting using subplots
##################################
plt.figure(figsize=(15, 5))

##################################
# Formulating the original image
##################################
plt.subplot(1, 4, 1)
plt.imshow(image)
plt.title('Original Image', fontsize = 14, weight = 'bold')
plt.axis('off')

##################################
# Formulating the blue channel
##################################
plt.subplot(1, 4, 2)
plt.imshow(image[ : , : , 0])
plt.title('Blue Channel', fontsize = 14, weight = 'bold')
plt.axis('off')

##################################
# Formulating the green channel
##################################
plt.subplot(1, 4, 3)
plt.imshow(image[ : , : , 1])
plt.title('Green Channel', fontsize = 14, weight = 'bold')
plt.axis('off')

##################################
# Formulating the red channel
##################################
plt.subplot(1, 4, 4)
plt.imshow(image[ : , : , 2])
plt.title('Red Channel', fontsize = 14, weight = 'bold')
plt.axis('off')

##################################
# Consolidating all images
##################################
plt.show()
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In [23]:
##################################
# Determining the image shape
##################################
print('Image Shape:')
display(image.shape)

Image Shape:

(512, 512, 3)
In [24]:
##################################
# Determining the image height
##################################
print('Image Height:')
display(image.shape[0])

Image Height:

512
In [25]:
##################################
# Determining the image width
##################################
print('Image Width:')
display(image.shape[1])

Image Width:

512
In [26]:
##################################
# Determining the image dimension
##################################
print('Image Dimension:')
display(image.ndim)

Image Dimension:

3
In [27]:
##################################
# Determining the image size
##################################
print('Image Size:')
display(image.size)

Image Size:

786432
In [28]:
##################################
# Determining the image data type
##################################
print('Image Data Type:')
display(image.dtype)

Image Data Type:

dtype('uint8')
In [29]:
##################################
# Determining the maximum RGB value
##################################
print('Image Maximum RGB:')
display(image.max())

Image Maximum RGB:

np.uint8(255)
In [30]:
##################################
# Determining the minimum RGB value
##################################
print('Image Minimum RGB:')
display(image.min())

Image Minimum RGB:

np.uint8(0)
In [31]:
##################################
# Identifying the path for the images
# and defining image categories 
##################################
path = (os.path.join("..", DATASETS_FINAL_TRAIN_PATH))
classes=["notumor", "glioma", "meningioma", "pituitary"]
num_classes = len(classes)
batch_size = 16
In [32]:
##################################
# Creating subsets of images
# for model training and
# setting the parameters for
# real-time data augmentation
# at each epoch
##################################
set_seed()
train_datagen = ImageDataGenerator(rescale=1./255,
                                   rotation_range=5,
                                   width_shift_range=0.05,
                                   height_shift_range=0.05,
                                   horizontal_flip=True,
                                   vertical_flip=True,
                                   shear_range=0.05,
                                   zoom_range=0.05,
                                   validation_split=0.2)


##################################
# Loading the model training images
##################################
train_gen = train_datagen.flow_from_directory(directory=path, 
                                              target_size=(299, 299),
                                              class_mode='categorical',
                                              subset='training',
                                              shuffle=True, 
                                              classes=classes,
                                              batch_size=batch_size, 
                                              color_mode="grayscale")

Found 4571 images belonging to 4 classes.
In [33]:
##################################
# Loading samples of augmented images
# for the training set
##################################
##################################
# Loading samples of augmented images
# for the training set
##################################
fig, axes = plt.subplots(1, 5, figsize=(15, 3))

for i in range(5):
    batch = next(train_gen)
    images, labels = batch
    axes[i].imshow(images[0]) 
    axes[i].set_title(f"Label: {labels[0]}")
    axes[i].axis('off')
plt.show()
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In [34]:
##################################
# Creating subsets of images
# for model validation
# setting the parameters for
# real-time data augmentation
# at each epoch
##################################
set_seed()
test_datagen = ImageDataGenerator(rescale=1./255, 
                                  validation_split=0.2)

##################################
# Loading the model evaluation images
##################################
test_gen = test_datagen.flow_from_directory(directory=path, 
                                            target_size=(299, 299),
                                            class_mode='categorical',
                                            subset='validation',
                                            shuffle=False, 
                                            classes=classes,
                                            batch_size=batch_size, 
                                            color_mode="grayscale")

Found 1141 images belonging to 4 classes.
In [35]:
##################################
# Loading samples of original images
# for the validation set
##################################
images, labels = next(test_gen)
fig, axes = plt.subplots(1, 5, figsize=(15, 3))
for i, idx in enumerate(range(0, 5)):
    axes[i].imshow(images[idx])
    axes[i].set_title(f"Label: {labels[0]}")
    axes[i].axis('off')
plt.show()
No description has been provided for this image

1.5 Data Exploration ¶

1.5.1 Exploratory Data Analysis ¶

In [36]:
##################################
# Consolidating summary statistics
# for the image pixel values
##################################
mean_val = []
std_dev_val = []
max_val = []
min_val = []

for i in range(0, samples):
    mean_val.append(mri_images['Image'][i].mean())
    std_dev_val.append(np.std(mri_images['Image'][i]))
    max_val.append(mri_images['Image'][i].max())
    min_val.append(mri_images['Image'][i].min())

imageEDA = mri_images.loc[:,['Image', 'Class','Path']]
imageEDA['Mean'] = mean_val
imageEDA['StDev'] = std_dev_val
imageEDA['Max'] = max_val
imageEDA['Min'] = min_val
In [37]:
##################################
# Consolidating the overall mean
# for the pixel intensity means
# grouped by categories
##################################
imageEDA.groupby(['Class'])['Mean'].mean()
Out[37]:
Class
Glioma        32.716871
Meningioma    43.487954
No Tumor      60.815724
Pituitary     49.273456
Name: Mean, dtype: float64
In [38]:
##################################
# Consolidating the overall minimum
# for the pixel intensity means
# grouped by categories
##################################
imageEDA.groupby(['Class'])['Mean'].min()
Out[38]:
Class
Glioma        13.701850
Meningioma    18.233400
No Tumor       9.770775
Pituitary     24.699575
Name: Mean, dtype: float64
In [39]:
##################################
# Consolidating the overall maximum
# for the pixel intensity means
# grouped by categories
##################################
imageEDA.groupby(['Class'])['Mean'].max()
Out[39]:
Class
Glioma         68.372425
Meningioma    137.765375
No Tumor      125.066725
Pituitary     102.007950
Name: Mean, dtype: float64
In [40]:
##################################
# Consolidating the overall standard deviation
# for the pixel intensity means
# grouped by categories
##################################
imageEDA.groupby(['Class'])['Mean'].std()
Out[40]:
Class
Glioma         8.565834
Meningioma    14.307165
No Tumor      21.338225
Pituitary      8.222902
Name: Mean, dtype: float64
In [41]:
##################################
# Formulating the mean distribution
# by category of the image pixel values
##################################
sns.displot(data = imageEDA, x = 'Mean', kind="kde", hue = 'Class', height=6, aspect=1.40)
plt.title('Image Pixel Intensity Mean Distribution by Category', fontsize=14, weight='bold');
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In [42]:
##################################
# Formulating the maximum distribution
# by category of the image pixel values
##################################
sns.displot(data = imageEDA, x = 'Max', kind="kde", hue = 'Class', height=6, aspect=1.40)
plt.title('Image Pixel Intensity Maximum Distribution by Category', fontsize=14, weight='bold');
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In [43]:
##################################
# Formulating the minimum distribution
# by category of the image pixel values
##################################
sns.displot(data = imageEDA, x = 'Min', kind="kde", hue = 'Class', height=6, aspect=1.40)
plt.title('Image Pixel Intensity Minimum Distribution by Category', fontsize=14, weight='bold');
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In [44]:
##################################
# Formulating the standard deviation distribution
# by category of the image pixel values
##################################
sns.displot(data = imageEDA, x = 'StDev', kind="kde", hue = 'Class', height=6, aspect=1.40)
plt.title('Image Pixel Intensity Standard Deviation Distribution by Category', fontsize=14, weight='bold');
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In [45]:
##################################
# Formulating the mean and standard deviation 
# scatterplot distribution
# by category of the image pixel values
##################################
plt.figure(figsize=(10,6))
sns.set(style="ticks", font_scale = 1)
ax = sns.scatterplot(data=imageEDA, x="Mean", y=imageEDA['StDev'], hue='Class', alpha=0.5)
sns.despine(top=True, right=True, left=False, bottom=False)
plt.xticks(rotation=0, fontsize = 12)
ax.set_xlabel('Image Pixel Intensity Mean',fontsize=14, weight='bold')
ax.set_ylabel('Image Pixel Intensity Standard Deviation', fontsize=14, weight='bold')
plt.title('Image Pixel Intensity Mean and Standard Deviation Distribution', fontsize = 14, weight='bold');
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In [46]:
##################################
# Formulating the mean and standard deviation 
# scatterplot distribution
# by category of the image pixel values
##################################
scatterplot = sns.FacetGrid(imageEDA, col="Class", height=6)
scatterplot.map_dataframe(sns.scatterplot, x='Mean', y='StDev', alpha=0.5)
scatterplot.set_titles(col_template="{col_name}", row_template="{row_name}", size=18)
scatterplot.fig.subplots_adjust(top=.8)
scatterplot.fig.suptitle('Image Pixel Intensity Mean and Standard Deviation Distribution', fontsize=14, weight='bold')
axes = scatterplot.axes.flatten()
axes[0].set_ylabel('Image Pixel Intensity Standard Deviation')
for ax in axes:
    ax.set_xlabel('Image Pixel Intensity Mean')
scatterplot.fig.tight_layout()
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In [47]:
##################################
# Formulating the mean and standard deviation 
# scatterplot distribution
# of the image pixel values
# represented as actual images
##################################
def getImage(path):
    image = cv2.imread(path)
    resized_image = cv2.resize(image, (300,300))
    return OffsetImage(resized_image, zoom = 0.1)

DF_sample = imageEDA.sample(frac=1.0, replace=False, random_state=123)
paths = DF_sample['Path']

fig, ax = plt.subplots(figsize=(15,9))
ab = sns.scatterplot(data=DF_sample, x="Mean", y='StDev')
sns.despine(top=True, right=True, left=False, bottom=False)
ax.set_xlabel('Image Pixel Intensity Mean', fontsize=14, weight='bold')
ax.set_ylabel('Image Pixel Intensity Standard Deviation', fontsize=14, weight='bold')
ax.set_xlim(-5,145)
ax.set_ylim(0,120)
plt.title('Overall: Image Pixel Intensity Mean and Standard Deviation Distribution', fontsize=14, weight='bold');

for x0, y0, path in zip(DF_sample['Mean'], DF_sample['StDev'], paths):
    ab = AnnotationBbox(getImage(path), (x0, y0), frameon=False)
    ax.add_artist(ab)
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In [48]:
##################################
# Formulating the mean and standard deviation 
# scatterplot distribution
# of the image pixel values
# represented as actual images
# for the Glioma class
##################################
path_glioma = (os.path.join("..", DATASETS_FINAL_TRAIN_PATH,'glioma/'))
imageEDA_glioma = imageEDA.loc[imageEDA['Class'] == 'Glioma']

DF_sample = imageEDA_glioma.sample(frac=1.0, replace=False, random_state=123)
paths = DF_sample['Path']

fig, ax = plt.subplots(figsize=(15,9))
ab = sns.scatterplot(data=DF_sample, x="Mean", y='StDev')
sns.despine(top=True, right=True, left=False, bottom=False)
ax.set_xlabel('Image Pixel Intensity Mean', fontsize=14, weight='bold')
ax.set_ylabel('Image Pixel Intensity Standard Deviation', fontsize=14, weight='bold')
ax.set_xlim(-5,145)
ax.set_ylim(10,110)
plt.title('Glioma: Image Pixel Intensity Mean and Standard Deviation Distribution', fontsize=14, weight='bold');

for x0, y0, path_glioma in zip(DF_sample['Mean'], DF_sample['StDev'], paths):
    ab = AnnotationBbox(getImage(path_glioma), (x0, y0), frameon=False)
    ax.add_artist(ab)
No description has been provided for this image
In [49]:
##################################
# Formulating the mean and standard deviation 
# scatterplot distribution
# of the image pixel values
# represented as actual images
# for the Viral Pneumonia class
##################################
path_meningioma = (os.path.join("..", DATASETS_FINAL_TRAIN_PATH,'meningioma/'))
imageEDA_meningioma = imageEDA.loc[imageEDA['Class'] == 'Meningioma']

DF_sample = imageEDA_meningioma.sample(frac=1.0, replace=False, random_state=123)
paths = DF_sample['Path']

fig, ax = plt.subplots(figsize=(15,9))
ab = sns.scatterplot(data=DF_sample, x="Mean", y='StDev')
sns.despine(top=True, right=True, left=False, bottom=False)
ax.set_xlabel('Image Pixel Intensity Mean', fontsize=14, weight='bold')
ax.set_ylabel('Image Pixel Intensity Standard Deviation', fontsize=14, weight='bold')
ax.set_xlim(-5,145)
ax.set_ylim(10,110)
plt.title('Meningioma: Image Pixel Intensity Mean and Standard Deviation Distribution', fontsize=14, weight='bold');

for x0, y0, path_meningioma in zip(DF_sample['Mean'], DF_sample['StDev'], paths):
    ab = AnnotationBbox(getImage(path_meningioma), (x0, y0), frameon=False)
    ax.add_artist(ab)
No description has been provided for this image
In [50]:
##################################
# Formulating the mean and standard deviation 
# scatterplot distribution
# of the image pixel values
# represented as actual images
# for the Pituitary class
##################################
path_pituitary = (os.path.join("..", DATASETS_FINAL_TRAIN_PATH,'pituitary/'))
imageEDA_pituitary = imageEDA.loc[imageEDA['Class'] == 'Pituitary']

DF_sample = imageEDA_pituitary.sample(frac=1.0, replace=False, random_state=123)
paths = DF_sample['Path']

fig, ax = plt.subplots(figsize=(15,9))
ab = sns.scatterplot(data=DF_sample, x="Mean", y='StDev')
sns.despine(top=True, right=True, left=False, bottom=False)
ax.set_xlabel('Image Pixel Intensity Mean', fontsize=14, weight='bold')
ax.set_ylabel('Image Pixel Intensity Standard Deviation', fontsize=14, weight='bold')
ax.set_xlim(0, 140)
ax.set_ylim(10,110)
plt.title('Pituitary: Image Pixel Intensity Mean and Standard Deviation Distribution', fontsize=14, weight='bold');

for x0, y0, path_pituitary in zip(DF_sample['Mean'], DF_sample['StDev'], paths):
    ab = AnnotationBbox(getImage(path_pituitary), (x0, y0), frameon=False)
    ax.add_artist(ab)
No description has been provided for this image
In [51]:
##################################
# Formulating the mean and standard deviation 
# scatterplot distribution
# of the image pixel values
# represented as actual images
# for the No Tumor class
##################################
path_no_tumor = (os.path.join("..", DATASETS_FINAL_TRAIN_PATH,'notumor/'))
imageEDA_no_tumor = imageEDA.loc[imageEDA['Class'] == 'No Tumor']

DF_sample = imageEDA_no_tumor.sample(frac=1.0, replace=False, random_state=123)
paths = DF_sample['Path']

fig, ax = plt.subplots(figsize=(15,9))
ab = sns.scatterplot(data=DF_sample, x="Mean", y='StDev')
sns.despine(top=True, right=True, left=False, bottom=False)
ax.set_xlabel('Image Pixel Intensity Mean', fontsize=14, weight='bold')
ax.set_ylabel('Image Pixel Intensity Standard Deviation', fontsize=14, weight='bold')
ax.set_xlim(-5,145)
ax.set_ylim(10,110)
plt.title('No Tumor: Image Pixel Intensity Mean and Standard Deviation Distribution', fontsize=14, weight='bold');

for x0, y0, path_no_tumor in zip(DF_sample['Mean'], DF_sample['StDev'], paths):
    ab = AnnotationBbox(getImage(path_no_tumor), (x0, y0), frameon=False)
    ax.add_artist(ab)
No description has been provided for this image
In [52]:
#################################
# Formulating the minimum and standard deviation 
# scatterplot distribution
# of the image pixel values
# represented as actual images
##################################
DF_sample = imageEDA.sample(frac=1.0, replace=False, random_state=123)
paths = DF_sample['Path']

fig, ax = plt.subplots(figsize=(15,9))
ab = sns.scatterplot(data=DF_sample, x="Min", y='StDev')
sns.despine(top=True, right=True, left=False, bottom=False)
ax.set_xlabel('Image Pixel Intensity Minimum', fontsize=14, weight='bold')
ax.set_ylabel('Image Pixel Intensity Standard Deviation', fontsize=14, weight='bold')
ax.set_xlim(-5,145)
ax.set_ylim(0,120)
plt.title('Overall: Image Pixel Intensity Minimum and Standard Deviation Distribution', fontsize=14, weight='bold');

for x0, y0, path in zip(DF_sample['Min'], DF_sample['StDev'], paths):
    ab = AnnotationBbox(getImage(path), (x0, y0), frameon=False)
    ax.add_artist(ab)
No description has been provided for this image
In [53]:
##################################
# Formulating the minimum and standard deviation 
# scatterplot distribution
# of the image pixel values
# represented as actual images
# for the Glioma class
##################################
DF_sample = imageEDA_glioma.sample(frac=1.0, replace=False, random_state=123)
paths = DF_sample['Path']

fig, ax = plt.subplots(figsize=(15,9))
ab = sns.scatterplot(data=DF_sample, x="Min", y='StDev')
sns.despine(top=True, right=True, left=False, bottom=False)
ax.set_xlabel('Image Pixel Intensity Minimum', fontsize=14, weight='bold')
ax.set_ylabel('Image Pixel Intensity Standard Deviation', fontsize=14, weight='bold')
ax.set_xlim(-5,145)
ax.set_ylim(10,110)
plt.title('Glioma: Image Pixel Intensity Minimum and Standard Deviation Distribution', fontsize=14, weight='bold');

for x0, y0, path_glioma in zip(DF_sample['Min'], DF_sample['StDev'], paths):
    ab = AnnotationBbox(getImage(path_glioma), (x0, y0), frameon=False)
    ax.add_artist(ab)
No description has been provided for this image
In [54]:
##################################
# Formulating the minimum and standard deviation 
# scatterplot distribution
# of the image pixel values
# represented as actual images
# for the Meningioma class
##################################
DF_sample = imageEDA_meningioma.sample(frac=1.0, replace=False, random_state=123)
paths = DF_sample['Path']

fig, ax = plt.subplots(figsize=(15,9))
ab = sns.scatterplot(data=DF_sample, x="Min", y='StDev')
sns.despine(top=True, right=True, left=False, bottom=False)
ax.set_xlabel('Image Pixel Intensity Minimum', fontsize=14, weight='bold')
ax.set_ylabel('Image Pixel Intensity Standard Deviation', fontsize=14, weight='bold')
ax.set_xlim(-5,145)
ax.set_ylim(10,110)
plt.title('Meningioma: Image Pixel Intensity Minimum and Standard Deviation Distribution', fontsize=14, weight='bold');

for x0, y0, path_meningioma in zip(DF_sample['Min'], DF_sample['StDev'], paths):
    ab = AnnotationBbox(getImage(path_meningioma), (x0, y0), frameon=False)
    ax.add_artist(ab)
No description has been provided for this image
In [55]:
##################################
# Formulating the minimum and standard deviation 
# scatterplot distribution
# of the image pixel values
# represented as actual images
# for the Pituitary class
##################################
DF_sample = imageEDA_pituitary.sample(frac=1.0, replace=False, random_state=123)
paths = DF_sample['Path']

fig, ax = plt.subplots(figsize=(15,9))
ab = sns.scatterplot(data=DF_sample, x="Min", y='StDev')
sns.despine(top=True, right=True, left=False, bottom=False)
ax.set_xlabel('Image Pixel Intensity Minimum', fontsize=14, weight='bold')
ax.set_ylabel('Image Pixel Intensity Standard Deviation', fontsize=14, weight='bold')
ax.set_xlim(-5,145)
ax.set_ylim(10,110)
plt.title('Pituitary: Image Pixel Intensity Minimum and Standard Deviation Distribution', fontsize=14, weight='bold');

for x0, y0, path_pituitary in zip(DF_sample['Min'], DF_sample['StDev'], paths):
    ab = AnnotationBbox(getImage(path_pituitary), (x0, y0), frameon=False)
    ax.add_artist(ab)
No description has been provided for this image
In [56]:
##################################
# Formulating the minimum and standard deviation 
# scatterplot distribution
# of the image pixel values
# represented as actual images
# for the No Tumor class
##################################
DF_sample = imageEDA_no_tumor.sample(frac=1.0, replace=False, random_state=123)
paths = DF_sample['Path']

fig, ax = plt.subplots(figsize=(15,9))
ab = sns.scatterplot(data=DF_sample, x="Min", y='StDev')
sns.despine(top=True, right=True, left=False, bottom=False)
ax.set_xlabel('Image Pixel Intensity Minimum', fontsize=14, weight='bold')
ax.set_ylabel('Image Pixel Intensity Standard Deviation', fontsize=14, weight='bold')
ax.set_xlim(-5,145)
ax.set_ylim(10,110)
plt.title('No Tumor: Image Pixel Intensity Minimum and Standard Deviation Distribution', fontsize=14, weight='bold');

for x0, y0, path_no_tumor in zip(DF_sample['Min'], DF_sample['StDev'], paths):
    ab = AnnotationBbox(getImage(path_no_tumor), (x0, y0), frameon=False)
    ax.add_artist(ab)
No description has been provided for this image
In [57]:
#################################
# Formulating the maximum and standard deviation 
# scatterplot distribution
# of the image pixel values
# represented as actual images
##################################
DF_sample = imageEDA.sample(frac=1.0, replace=False, random_state=123)
paths = DF_sample['Path']

fig, ax = plt.subplots(figsize=(15,9))
ab = sns.scatterplot(data=DF_sample, x="Max", y='StDev')
sns.despine(top=True, right=True, left=False, bottom=False)
ax.set_xlabel('Image Pixel Intensity Maximum', fontsize=14, weight='bold')
ax.set_ylabel('Image Pixel Intensity Standard Deviation', fontsize=14, weight='bold')
ax.set_xlim(115,265)
ax.set_ylim(0,120)
plt.title('Overall: Image Pixel Intensity Maximum and Standard Deviation Distribution', fontsize=14, weight='bold');

for x0, y0, path in zip(DF_sample['Max'], DF_sample['StDev'], paths):
    ab = AnnotationBbox(getImage(path), (x0, y0), frameon=False)
    ax.add_artist(ab)
No description has been provided for this image
In [58]:
##################################
# Formulating the maximum and standard deviation 
# scatterplot distribution
# of the image pixel values
# represented as actual images
# for the Glioma class
##################################
DF_sample = imageEDA_glioma.sample(frac=1.0, replace=False, random_state=123)
paths = DF_sample['Path']

fig, ax = plt.subplots(figsize=(15,9))
ab = sns.scatterplot(data=DF_sample, x="Max", y='StDev')
sns.despine(top=True, right=True, left=False, bottom=False)
ax.set_xlabel('Image Pixel Intensity Maximum', fontsize=14, weight='bold')
ax.set_ylabel('Image Pixel Intensity Standard Deviation', fontsize=14, weight='bold')
ax.set_xlim(115,265)
ax.set_ylim(10,110)
plt.title('Glioma: Image Pixel Intensity Maximum and Standard Deviation Distribution', fontsize=14, weight='bold');

for x0, y0, path_glioma in zip(DF_sample['Max'], DF_sample['StDev'], paths):
    ab = AnnotationBbox(getImage(path_glioma), (x0, y0), frameon=False)
    ax.add_artist(ab)
No description has been provided for this image
In [59]:
##################################
# Formulating the maximum and standard deviation 
# scatterplot distribution
# of the image pixel values
# represented as actual images
# for the Meningioma class
##################################
DF_sample = imageEDA_meningioma.sample(frac=1.0, replace=False, random_state=123)
paths = DF_sample['Path']

fig, ax = plt.subplots(figsize=(15,9))
ab = sns.scatterplot(data=DF_sample, x="Max", y='StDev')
sns.despine(top=True, right=True, left=False, bottom=False)
ax.set_xlabel('Image Pixel Intensity Maximum', fontsize=14, weight='bold')
ax.set_ylabel('Image Pixel Intensity Standard Deviation', fontsize=14, weight='bold')
ax.set_xlim(115,265)
ax.set_ylim(10,110)
plt.title('Meningioma: Image Pixel Intensity Maximum and Standard Deviation Distribution', fontsize=14, weight='bold');

for x0, y0, path_meningioma in zip(DF_sample['Max'], DF_sample['StDev'], paths):
    ab = AnnotationBbox(getImage(path_meningioma), (x0, y0), frameon=False)
    ax.add_artist(ab)
No description has been provided for this image
In [60]:
##################################
# Formulating the maximum and standard deviation 
# scatterplot distribution
# of the image pixel values
# represented as actual images
# for the Pituitary class
##################################
DF_sample = imageEDA_pituitary.sample(frac=1.0, replace=False, random_state=123)
paths = DF_sample['Path']

fig, ax = plt.subplots(figsize=(15,9))
ab = sns.scatterplot(data=DF_sample, x="Max", y='StDev')
sns.despine(top=True, right=True, left=False, bottom=False)
ax.set_xlabel('Image Pixel Intensity Maximum', fontsize=14, weight='bold')
ax.set_ylabel('Image Pixel Intensity Standard Deviation', fontsize=14, weight='bold')
ax.set_xlim(115,265)
ax.set_ylim(10,110)
plt.title('Pituitary: Image Pixel Intensity Maximum and Standard Deviation Distribution', fontsize=14, weight='bold');

for x0, y0, path_pituitary in zip(DF_sample['Max'], DF_sample['StDev'], paths):
    ab = AnnotationBbox(getImage(path_pituitary), (x0, y0), frameon=False)
    ax.add_artist(ab)
No description has been provided for this image
In [61]:
##################################
# Formulating the maximum and standard deviation 
# scatterplot distribution
# of the image pixel values
# represented as actual images
# for the No Tumor class
##################################
DF_sample = imageEDA_no_tumor.sample(frac=1.0, replace=False, random_state=123)
paths = DF_sample['Path']

fig, ax = plt.subplots(figsize=(15,9))
ab = sns.scatterplot(data=DF_sample, x="Max", y='StDev')
sns.despine(top=True, right=True, left=False, bottom=False)
ax.set_xlabel('Image Pixel Intensity Maximum', fontsize=14, weight='bold')
ax.set_ylabel('Image Pixel Intensity Standard Deviation', fontsize=14, weight='bold')
ax.set_xlim(115,265)
ax.set_ylim(10,110)
plt.title('No Tumor: Image Pixel Intensity Maximum and Standard Deviation Distribution', fontsize=14, weight='bold');

for x0, y0, path_no_tumor in zip(DF_sample['Max'], DF_sample['StDev'], paths):
    ab = AnnotationBbox(getImage(path_no_tumor), (x0, y0), frameon=False)
    ax.add_artist(ab)
No description has been provided for this image

1.5.2 Hypothesis Testing ¶

1.6 Predictive Model Development ¶

1.6.1 Pre-Modelling Data Preparation ¶

1.6.2 Data Splitting ¶

1.6.3 Convolutional Neural Network Sequential Layer Development ¶

1.6.3.1 CNN With No Regularization ¶

1.6.3.2 CNN With Dropout Regularization ¶

1.6.3.3 CNN With Batch Normalization Regularization ¶

1.6.3.4 CNN With Dropout and Batch Normalization Regularization ¶

1.6.4 CNN With No Regularization Model Fitting | Hyperparameter Tuning | Validation ¶

1.6.5 CNN With Dropout Regularization Model Fitting | Hyperparameter Tuning | Validation ¶

1.6.6 CNN With Batch Normalization Regularization Model Fitting | Hyperparameter Tuning | Validation ¶

1.6.7 CNN With Dropout and Batch Normalization Regularization Model Fitting | Hyperparameter Tuning | Validation ¶

1.6.8 Model Selection ¶

1.6.9 Model Testing ¶

1.6.10 Model Inference ¶

1.7 Predictive Model Development ¶

1.7.1 Model Application Programming Interface Code Development ¶

1.7.2 User Interface Application Code Development ¶

1.7.3 Web Application ¶

2. Summary ¶

3. References ¶

  • [Book] Deep Learning with Python by Francois Chollet
  • [Book] Deep Learning: A Visual Approach by Andrew Glassner
  • [Book] Learning Deep Learning by Magnus Ekman
  • [Book] Practical Deep Learning by Ronald Kneusel
  • [Book] Deep Learning with Tensorflow and Keras by Amita Kapoor, Antonio Gulli and Sujit Pal
  • [Book] Deep Learning by John Kelleher
  • [Book] Generative Deep Learning by David Foster
  • [Book] Deep Learning Illustrated by John Krohn, Grant Beyleveld and Aglae Bassens
  • [Book] Neural Networks and Deep Learning by Charu Aggarwal
  • [Book] Grokking Deep Learning by Andrew Trask
  • [Book] Deep Learning with Pytorch by Eli Stevens, Luca Antiga and Thomas Viehmann
  • [Book] Deep Learning by Ian Goodfellow, Yoshua Bengio and Aaron Courville
  • [Book] Deep Learning from Scratch by Seth Weidman
  • [Book] Fundamentals of Deep Learning by Nithin Buduma, Nikhil Buduma and Joe Papa
  • [Book] Hands-On Machine Learning with Scikit-Learn, Keras and Tensorflow by Aurelien Geron
  • [Book] Deep Learning for Computer Vision by Jason Brownlee
  • [Python Library API] numpy by NumPy Team
  • [Python Library API] pandas by Pandas Team
  • [Python Library API] seaborn by Seaborn Team
  • [Python Library API] matplotlib.pyplot by MatPlotLib Team
  • [Python Library API] matplotlib.image by MatPlotLib Team
  • [Python Library API] matplotlib.offsetbox by MatPlotLib Team
  • [Python Library API] tensorflow by TensorFlow Team
  • [Python Library API] keras by Keras Team
  • [Python Library API] pil by Pillow Team
  • [Python Library API] glob by glob Team
  • [Python Library API] cv2 by OpenCV Team
  • [Python Library API] os by os Team
  • [Python Library API] random by random Team
  • [Python Library API] keras.models by TensorFlow Team
  • [Python Library API] keras.layers by TensorFlow Team
  • [Python Library API] keras.wrappers by TensorFlow Team
  • [Python Library API] keras.utils by TensorFlow Team
  • [Python Library API] keras.optimizers by TensorFlow Team
  • [Python Library API] keras.preprocessing.image by TensorFlow Team
  • [Python Library API] keras.callbacks by TensorFlow Team
  • [Python Library API] keras.metrics by TensorFlow Team
  • [Python Library API] sklearn.metrics by Scikit-Learn Team
  • [Article] Convolutional Neural Networks, Explained by Mayank Mishra (Towards Data Science)
  • [Article] A Comprehensive Guide to Convolutional Neural Networks — the ELI5 way by Sumit Saha (Towards Data Science)
  • [Article] Understanding Convolutional Neural Networks: A Beginner’s Journey into the Architecture by Afaque Umer (Medium)
  • [Article] Introduction to Convolutional Neural Networks (CNN) by Manav Mandal (Analytics Vidhya)
  • [Article] What Are Convolutional Neural Networks? by IBM Team (IBM)
  • [Article] What is CNN? A 5 Year Old guide to Convolutional Neural Network by William Ong (Medium)
  • [Article] Convolutional Neural Network by Thomas Wood (DeepAI.Org)
  • [Article] How Do Convolutional Layers Work in Deep Learning Neural Networks? by Jason Brownlee (Machine Learning Mastery)
  • [Article] Convolutional Neural Networks Explained: Using PyTorch to Understand CNNs by Vihar Kurama (BuiltIn)
  • [Article] Convolutional Neural Networks Cheatsheet by Afshine Amidi and Shervine Amidi (Stanford University)
  • [Article] An Intuitive Explanation of Convolutional Neural Networks by Ujjwal Karn (The Data Science Blog)
  • [Article] Convolutional Neural Network by NVIDIA Team (NVIDIA)
  • [Article] Convolutional Neural Networks (CNN) Overview by Nikolaj Buhl (Encord)
  • [Article] Understanding Convolutional Neural Network (CNN): A Complete Guide by LearnOpenCV Team (LearnOpenCV)
  • [Article] Convolutional Neural Networks (CNNs) and Layer Types by Adrian Rosebrock (PyImageSearch)
  • [Article] How Convolutional Neural Networks See The World by Francois Chollet (The Keras Blog)
  • [Article] What Is a Convolutional Neural Network? by MathWorks Team (MathWorks)
  • [Article] Grad-CAM Class Activation Visualization by Francois Chollet (Keras.IO)
  • [Article] Grad-CAM: Visualize Class Activation Maps with Keras, TensorFlow, and Deep Learning by Adrian Rosebrock (PyImageSearch)
  • [Kaggle Project] glioma 19 Radiography Data - EDA and CNN Model by Juliana Negrini De Araujo (Kaggle)
  • [Kaggle Project] Pneumonia Detection using CNN (92.6% Accuracy) by Madhav Mathur (Kaggle)
  • [Kaggle Project] glioma Detection from CXR Using Explainable CNN by Manu Siddhartha (Kaggle)
  • [Kaggle Project] Class Activation Mapping for glioma-19 CNN by Amy Zhang (Kaggle)
  • [Kaggle Project] CNN mri glioma Classification by Gabriel Mino (Kaggle)
  • [Kaggle Project] Detecting-glioma-19-Images | CNN by Felipe Oliveira (Kaggle)
  • [Kaggle Project] Detection of glioma Positive Cases using DL by Sana Shaikh (Kaggle)
  • [Kaggle Project] Deep Learning and Transfer Learning on glioma-19 by Digvijay Yadav (Kaggle)
  • [Kaggle Project] X-ray Detecting Using CNN by Shivan Kumar (Kaggle)
  • [Kaggle Project] Classification of glioma-19 using CNN by Islam Selim (Kaggle)
  • [Kaggle Project] glioma-19 - Revisiting Pneumonia Detection by Paulo Breviglieri (Kaggle)
  • [Kaggle Project] Multi-Class X-ray glioma19 Classification-94% Accurary by Quadeer Shaikh (Kaggle)
  • [Kaggle Project] Grad-CAM: What Do CNNs See? by Derrel Souza (Kaggle)
  • [GitHub Project] Grad-CAM by Ismail Uddin (GitHub)
  • [Publication] Gradient-Based Learning Applied to Document Recognition by Yann LeCun, Leon Bottou, Yoshua Bengio and Patrick Haffner (Proceedings of the IEEE)
  • [Publication] Learning Deep Features for Discriminative Localization by Bolei Zhou, Aditya Khosla, Agata Lapedriza, Aude Oliva and Antonio Torralba (Computer Vision and Pattern Recognition)
  • [Publication] Grad-CAM: Visual Explanations from Deep Networks via Gradient-based Localization by Ramprasaath Selvaraju, Michael Cogswell, Abhishek Das, Ramakrishna Vedantam, Devi Parikh and Dhruv Batra (Computer Vision and Pattern Recognition)
  • [Course] IBM Data Analyst Professional Certificate by IBM Team (Coursera)
  • [Course] IBM Data Science Professional Certificate by IBM Team (Coursera)
  • [Course] IBM Machine Learning Professional Certificate by IBM Team (Coursera)
In [62]:
from IPython.display import display, HTML
display(HTML("<style>.rendered_html { font-size: 15px; font-family: 'Trebuchet MS'; }</style>"))